Shoukat Dedhar: search on Z-Library

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1

A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors

McDonald, Paul C., Chia, Stephen, Bedard, Philippe L., Chu, Quincy, Lyle, Michael, Tang, Liren, Singh, Madhu, Zhang, Zaihui, Supuran, Claudiu T., Renouf, Daniel J., Dedhar, Shoukat

Journal:

American Journal of Clinical Oncology

Year:

2020

File:

PDF, 219 KB

2020

2

Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling

Shoukat Dedhar, Benjamin Williams, Gregory Hannigan

Journal:

Trends in Cell Biology

Year:

1999

Language:

english

File:

PDF, 348 KB

english, 1999

3

Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy

Chen, Hua, Huang, Xueyin N, Yan, Wen, Chen, Ka, Guo, Lida, Tummalapali, Lekha, Dedhar, Shoukat, St-Arnaud, René, Wu, Chuanyue, Sepulveda, Jorge L

Journal:

Laboratory Investigation

Year:

2005

Language:

english

File:

PDF, 659 KB

english, 2005

4

Integrin-linked kinase: a cancer therapeutic target unique among its ILK

Hannigan, Gregory, Troussard, Armelle A., Dedhar, Shoukat

Journal:

Nature Reviews Cancer

Year:

2005

Language:

english

File:

PDF, 290 KB

english, 2005

5

The integrin-linked kinase (ILK) suppresses anoikis

Attwell, Sarah, Roskelley, Calvin, Dedhar, Shoukat

Journal:

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

6

2-[18F]Fluoroethanol and 3-[18F]fluoropropanol: facile preparation, biodistribution in mice, and their application as nucleophiles in the synthesis of [18F]fluoroalkyl aryl ester and ether PET tracers

Pan, Jinhe, Pourghiasian, Maral, Hundal, Navjit, Lau, Joseph, Bénard, François, Dedhar, Shoukat, Lin, Kuo-Shyan

Journal:

Nuclear Medicine and Biology

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

7

Cell Adhesion and the Integrin-Linked Kinase Regulate the LEF-1 and β -catenin Signaling Pathways

Anton Novak, Shu-Chi Hsu, Chungyee Leung-Hagesteijn, Galina Radeva, Jackie Papkoff, Roberto Montesano, Calvin Roskelley, Rudolf Grosschedl and Shoukat Dedhar

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.86 MB

english, 1998

8

Reduced Contact-Inhibition and Substratum Adhesion in Epithelial Cells Expressing GlcNAc-Transferase V

Michael Demetriou, Ivan R. Nabi, Marc Coppolino, Shoukat Dedhar and James W. Dennis

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 2.28 MB

english, 1995

9

Carving out its niche: A role for Carbonic Anhydrase IX in pre-metastatic niche development

Chafe, Shawn C., Dedhar, Shoukat

Journal:

Year:

2015

Language:

english

File:

PDF, 2.34 MB

english, 2015

10

Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells

Barberà, Maria José, Puig, Isabel, Domínguez, David, Julien-Grille, Sylvia, Guaita-Esteruelas, Sandra, Peiró, Sandra, Baulida, Josep, Francí, Clara, Dedhar, Shoukat, Larue, Lionel

Journal:

Year:

2004

Language:

english

File:

PDF, 484 KB

english, 2004

11

Isolation of a Novel Integrin Receptor Mediating ARG-GLY-ASP-Directed Cell Adhesion to Fibronectin and Type I Collagen from Human Neuroblastoma Cells. Association of a Novel β1-Related Subunit with αv

Shoukat Dedhar and Virginia Gray

Journal:

The Journal of Cell Biology

Year:

1990

Language:

english

File:

PDF, 974 KB

english, 1990

12

Epithelial-Mesenchymal Transitions – New Insights into Signaling, Development and Pathogenesis

Thompson, Erik W., Savagner, Pierre, Dedhar, Shoukat, Kalluri, Raghu

Journal:

Cells Tissues Organs

Year:

2007

Language:

english

File:

PDF, 67 KB

english, 2007

13

Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides As SLC-0111 Analogues For the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX

Bozdag, Murat, Carta, Fabrizio, Ceruso, Mariangela, Ferraroni, Marta, McDonald, Paul C., Dedhar, Shoukat, Supuran, Claudiu T

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 963 KB

english, 2018

14

Î²1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells

Mousavizadeh, Rouhollah, Hojabrpour, Payman, Eltit, Felipe, McDonald, Paul C., Dedhar, Shoukat, McCormack, Robert G., Duronio, Vincent, Jafarnejad, Seyed Mehdi, Scott, Alex

Journal:

Scientific Reports

Year:

2020

File:

PDF, 8.91 MB

2020

15

Combined inhibition of integrin linked kinase and FMS-like tyrosine kinase 3 is cytotoxic to acute myeloid leukemia progenitor cells

Andrew L. Muranyi, Shoukat Dedhar, Donna E. Hogge

Journal:

Experimental Hematology

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

16

Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors

Touisni, Nadia, Maresca, Alfonso, McDonald, Paul C., Lou, Yuanmei, Scozzafava, Andrea, Dedhar, Shoukat, Winum, Jean-Yves, Supuran, Claudiu T.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

17

Integrin-Linked Kinase Regulates Interphase and Mitotic Microtubule Dynamics

Lim, Simin, Kawamura, Eiko, Fielding, Andrew B., Maydan, Mykola, Dedhar, Shoukat, Marcus, Adam I.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.30 MB

english, 2013

18

ILK (integrin-linked kinase)

Serrano, Isabel, McDonald, Paul, Dedhar, Shoukat

Journal:

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Year:

2017

Language:

english

File:

PDF, 376 KB

english, 2017

19

Targeting integrin linked kinase and FMS-like tyrosine kinase-3 is cytotoxic to acute myeloid leukemia stem cells but spares normal progenitors

Andrew L. Muranyi, Shoukat Dedhar, Donna E. Hogge

Journal:

Leukemia Research

Year:

2010

Language:

english

File:

PDF, 270 KB

english, 2010

20

Paxillin phosphorylation: bifurcation point downstream of integrin-linked kinase (ILK) in streptococcal invasion

Beinan Wang, Shaoying Li, Shoukat Dedhar, P. Patrick Cleary

Journal:

Cellular Microbiology

Year:

2007

Language:

english

File:

PDF, 422 KB

english, 2007

21

Inhibition of nuclear hormone receptor activity by calreticulin

Dedhar, Shoukat, Rennie, Paul S., Shago, Mary, Hagesteijn, Chung-Yee Leung, Yang, Huiling, Filmus, Jorge, Hawley, Robert G., Bruchovsky, Nicholas, Cheng, Helen, Matusik, Robert J.

Journal:

Year:

1994

File:

PDF, 667 KB

1994

22

ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling

Qian, Yong, Zhong, Xiaosong, Flynn, Daniel C, Zheng, Jenny Z, Qiao, Meng, Wu, Chuanyue, Dedhar, Shoukat, Shi, Xianglin, Jiang, Bing-Hua

Journal:

Year:

2005

Language:

english

File:

PDF, 474 KB

english, 2005

23

The Epithelial-Mesenchymal Transition: New Insights in Signaling, Development, and Disease

Jonathan M. Lee, Shoukat Dedhar, Raghu Kalluri and Erik W. Thompson

Journal:

The Journal of Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.51 MB

english, 2006

24

Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly

Vasiliki Gkretsi, Udayan Apte, Wendy M. Mars, William C. Bowen, Jian-Hua Luo, Yu Yang, Yan P. Yu, Ann Orr, René St.-Arnaud, Shoukat Dedhar, Klaus H. Kaestner, Chuanyue Wu, George K. Michalopoulos

Journal:

Year:

2008

Language:

english

File:

PDF, 455 KB

english, 2008

25

Methotrexate-resistant human promyelocytic leukemia (HL-60) cells express a dihydrofolate reductase with altered properties associated with increased enzyme activity

Shoukat Dedhar, James H. Goldie

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 689 KB

english, 1985

26

Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors

Rothe, Katharina, Babaian, Artem, Nakamichi, Naoto, Chen, Min, Chafe, Shawn C., Watanabe, Akie, Forrest, Donna L., Mager, Dixie L., Eaves, Connie J., Dedhar, Shoukat, Jiang, Xiaoyan

Journal:

Year:

2020

File:

PDF, 4.87 MB

2020

27

Cell–substrate interactions and signaling through ILK

Journal:

Current Opinion in Cell Biology

Year:

2000

Language:

english

File:

PDF, 95 KB

english, 2000

28

NGF-Induced Axon Growth Is Mediated by Localized Inactivation of GSK-3β and Functions of the Microtubule Plus End Binding Protein APC

Feng-Quan Zhou, Jiang Zhou, Shoukat Dedhar, Yao-Hong Wu, William D Snider

Journal:

Year:

2004

Language:

english

File:

PDF, 2.76 MB

english, 2004

29

Role of the integrin-linked kinase (ILK) in determining neuronal polarity

Wei Guo, Hui Jiang, Virginia Gray, Shoukat Dedhar, Yi Rao

Journal:

Developmental Biology

Year:

2007

Language:

english

File:

PDF, 2.06 MB

english, 2007

30

Human Granulocyte-Macrophage Colony-Stimulating Factor is a Growth Factor Active on a Variety of Cell Types of Nonhemopoietic Origin

Shoukat Dedhar, Louis Gaboury, Paula Galloway and Connie Eaves

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 790 KB

english, 1988

31

A Cell Surface Receptor Complex for Collagen Type I Recognizes the Arg-Gly-Asp Sequence

Shoukat Dedhar, Erkki Ruoslahti and Michael D. Pierschbacher

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 2.05 MB

english, 1987

32

Synthesis and evaluation of 18 F-labeled carbonic anhydrase IX inhibitors for imaging with positron emission tomography

Pan, Jinhe, Lau, Joseph, Mesak, Felix, Hundal, Navjit, Pourghiasian, Maral, Liu, Zhibo, Bénard, François, Dedhar, Shoukat, Supuran, Claudiu T., Lin, Kuo-Shyan

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 996 KB

english, 2014

33

Conditional Integrin-Linked Kinase Knockout in Epithelial Cells Reveals a Unique Phenotype With Simultaneously Enhanced Proliferation and Apoptosis

Kiran Assi, David A. Owen, Shoukat Dedhar, Baljinder Salh

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 83 KB

english, 2011

34

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

Barakat, Badia, Yu, Liang, Lo, Camden, Vu, Duc, De Luca, Elisabetta, Cain, Jason E, Martellotto, Luciano G, Dedhar, Shoukat, Sadler, Anthony J, Wang, Die, Neil Watkins, D, Hannigan, Gregory E

Journal:

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

35

Integrin-Linked Kinase (ILK) and Its Interactors: A New Paradigm for the Coupling of Extracellular Matrix to Actin Cytoskeleton and Signaling Complexes

Chuanyue Wu and Shoukat Dedhar

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 1.77 MB

english, 2001

36

Tumor Suppressor PTEN Inhibits Nuclear Accumulation of β-Catenin and T Cell/Lymphoid Enhancer Factor 1-Mediated Transcriptional Activation

Sujata Persad, Armelle A. Troussard, Timothy R. McPhee, David J. Mulholland and Shoukat Dedhar

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 4.71 MB

english, 2001

37

Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth

Edwards, Lincoln A, Thiessen, B, Dragowska, Wieslawa H, Daynard, Tim, Bally, Marcel B, Dedhar, Shoukat

Journal:

Year:

2005

Language:

english

File:

PDF, 488 KB

english, 2005

38

Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via α-PIX

Filipenko, Nolan R, Attwell, Sarah, Roskelley, Calvin, Dedhar, Shoukat

Journal:

Year:

2005

Language:

english

File:

PDF, 295 KB

english, 2005

39

Integrin-linked kinase (ILK): a “hot” therapeutic target

T.Nathan Yoganathan, Penny Costello, Xiaoyi Chen, Mojgan Jabali, Jun Yan, Dan Leung, Zaihui Zhang, Arthur Yee, Shoukat Dedhar, Jasbinder Sanghera

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 340 KB

english, 2000

40

Ligand-specific, transient interaction between integrins and calreticulin during cell adhesion to extracellular matrix proteins is dependent upon phosphorylation/dephosphorylation events

COPPOLINO, Marc G., DEDHAR, Shoukat

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 348 KB

english, 1999

41

Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction

McDonald, Paul C., Chafe, Shawn C., Dedhar, Shoukat

Journal:

Frontiers in Cell and Developmental Biology

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

42

Watch this intracellular space: Receptors for extracellular matrix edited by John A. McDonald and Robert P. Mecham, Academic Press, 1991. $69.95 (xiii + 330 pages) ISBN 0 12 483365 9

Journal:

Trends in Cell Biology

Year:

1993

Language:

english

File:

PDF, 330 KB

english, 1993

43

αv integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

Cruet-Hennequart, Séverine, Maubant, Sylvie, Luis, José, Gauduchon, Pascal, Staedel, Cathy, Dedhar, Shoukat

Journal:

Year:

2003

Language:

english

File:

PDF, 452 KB

english, 2003

44

Mammary epithelial-specific expression of the integrin linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice

White, Donald E, Cardiff, Robert D, Dedhar, Shoukat, Muller, William J

Journal:

Year:

2001

Language:

english

File:

PDF, 465 KB

english, 2001

45

Inactivation of the Integrin-Linked Kinase (ILK) in osteoblasts increases mineralization

Jad El-Hoss, Alice Arabian, Shoukat Dedhar, René St-Arnaud

Journal:

Year:

2008

Language:

english

File:

PDF, 82 KB

english, 2008

46

Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF)

Serrano, Isabel, Díez-Marqués, Maria L., Rodríguez-Puyol, Manuel, Herrero-Fresneda, Inmaculada, Raimundo García, del Moral, Dedhar, Shoukat, Ruiz-Torres, Maria P., Rodríguez-Puyol, Diego

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 1.94 MB

english, 2012

47

Alterations in Integrin Receptor Expression on Chemically Transformed Human Cells: Specific Enhancement of Laminin and Collagen Receptor Complexes

Shoukat Dedhar and Ronald Saulnier

Journal:

The Journal of Cell Biology

Year:

1990

Language:

english

File:

PDF, 1.47 MB

english, 1990

48

Integrin-Linked Kinase Localizes to the Centrosome and Regulates Mitotic Spindle Organization

Andrew B. Fielding, Iveta Dobreva, Paul C. McDonald, Leonard J. Foster and Shoukat Dedhar

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.37 MB

english, 2008

49

Epithelial–mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis

Yuanmei Lou, Olena Preobrazhenska, Ulrich auf dem Keller, Margaret Sutcliffe, Lorena Barclay, Paul C. McDonald, Calvin Roskelley, Christopher M. Overall, Shoukat Dedhar

Journal:

Developmental Dynamics

Year:

2008

Language:

english

File:

PDF, 9.93 MB

english, 2008

50

Integrin-linked kinase is an essential link between integrins and uptake of bacterial pathogens by epithelial cells

Beinan Wang, Ryan S. Yurecko, Shoukat Dedhar, P. Patrick Cleary

Journal:

Cellular Microbiology

Year:

2006

Language:

english

File:

PDF, 254 KB

english, 2006

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